Publications

Selected

Tsiantoulas, D. et al., 2021, APRIL limits atherosclerosis by binding to heparan-sulfate proteoglycans. Nature 2021 Sep ;597(7874):92-96. https://doi.org/10.1038/s41586-021-03818-3

Obermayer G*, Afonysuhkin T*, et al. Natural IgM antibodies inhibit microvesicle-driven coagulation and thrombosis. Blood 2020; Dec 9
https://pubmed.ncbi.nlm.nih.gov/33512411/

Alic L*, Papac-Milicevic N*, et al. A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes. Proc Natl Acad Sci U S A. 2020 May 5;117(18):9942-9951
https://pubmed.ncbi.nlm.nih.gov/32321835/

Puhm  F*,  Afonyushkin  T*, et  al. Mitochondria  are  a  subset  of extracellular vesicles released by activated monocytes and induce type I IFN and TNF responses in endothelial cells. Circ Res. 2019;125 (1), 43-52.https://pubmed.ncbi.nlm.nih.gov/31219742/

Tsiantoulas D, et al. B-Cell-Activating Factor Neutralization Aggravates Atherosclerosis. Circulation. 2018 Nov 13;138(20):2263-2273.
https://pubmed.ncbi.nlm.nih.gov/29858401/

Binder CJ, et al. Innate sensing of oxidation-specific epitopes in health and disease. Nat Rev Immunol. 2016;16(8):485-97.
https://pubmed.ncbi.nlm.nih.gov/27346802/

Gruber S, et al. Sialic Acid-Binding Immunoglobulin-like Lectin G Promotes Atherosclerosis and Liver Inflammation by Suppressing the Protective Functions of B-1 Cells. Cell Rep. 2016;14(10):2348-61.
https://pubmed.ncbi.nlm.nih.gov/26947073/

Cardilo-Reis L, et al. Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype. EMBO Mol Med. 2012 Oct;4(10):1072-86. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491837/

Weismann D, et al. Complement factor H binds malondialdehyde epitopes and protects from oxidative stress. Nature. 2011 Oct 5;478(7367):76-81. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826616/

Chou MY, et al. Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans. J Clin Invest. 2009 May;119(5):1335-49. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673862/

Binder CJ, et al. IL-5 links adaptive and natural immunity specific for epitopes of Oxidized LDL and protects from atherosclerosis. J Clin Invest 2004 Aug; 114(3):427-37. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC484976/

Binder CJ, et al. Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nat Med. 2003 Jun;9(6):736-43. http://www.nature.com/nm/journal/v9/n6/full/nm876.html?foxtrotcallback=true