Medical University of Vienna, Department of Laboratory Medicine, KILM Anna Spiegel Research Building Lazarettgasse 14, AKH BT25.2, Level6 1090 Vienna, Austria
Dimitrios Tsiantoulas studied molecular biology and genetics at the Democritus University of Thrace (Greece) and obtained his PhD degree from the Medical University of Vienna (Austria) in 2015, studying the impact of the immune system in atherosclerotic cardiovascular disease. He continued his training in immunity and atherosclerosis as a postdoctoral fellow, funded by the British Heart Foundation, in Prof. Ziad Mallat’s lab at the University of Cambridge. In 2019, he joined the Department of Laboratory Medicine at the Medical University of Vienna as a Group leader.
Know-how and research interests Heart attacks are the main causes of death worldwide. The main underlying pathology of this devastating condition is atherosclerosis, a lipid-driven chronic inflammatory disease that leads to the formation of an atherosclerotic plaque in large and medium size arteries. Plaque rupture or erosion triggers thrombus formation, which restricts blood flow in the artery, thereby limiting oxygen supply to the heart muscle and consequently causing myocardial cell necrosis. Dimitrios Tsiantoulas leads a research group that studies the role of the immune system in cardiovascular diseases, including atherosclerosis and myocardial infarction, and lipid metabolism.
Main Research Interests
Dissect the effect of B cell immunity in atherosclerosis and myocardial infarction
Investigate the function of APRIL (A Proliferation Inducing Ligand) in cardiovascular disease
Identify immunomodulatory therapies for cardiovascular diseases